Blastocystis Parasite Blog

Pages

  • Home
  • About This Blog
  • Site Map
  • Me and My Research
  • Financial Support for Blastocystis Research
  • Lab Stuff
  • CV
  • International Blastocystis Network
Showing posts with label T cells. Show all posts
Showing posts with label T cells. Show all posts

Friday, March 15, 2013

Immunology in the Gut Mucosa

Nice video!

Posted by Rune Stensvold at 9:40 PM No comments:
Email ThisBlogThis!Share to TwitterShare to FacebookShare to Pinterest
Labels: gut mucosa, ibd, immunity, Immunology, inflammation, neutrophils, T cells
Older Posts Home
Subscribe to: Posts (Atom)

On Blastocystis

Blastocystis is a protist parasitising the intestine of humans and a variety of animals. We estimate that at least 1 billion people worldwide are colonised by this parasite, most of whom probably experience no more episodes of intestinal upset, e.g. diarrhoea, than the average individual. In any case, many people have Blastocystis wihtout knowing and without feeling sick. Blastocystis may colonise the intestine for a long time (i.e. months or years).

Many species of Blastocystis have been acknowledged, of which at least 9 have been found in humans. Such species are currently termed "subtypes" (STs). ST1, ST2, ST3 and ST4 are common in Europe. While ST1, ST2, and ST3 appear to have equal prevalences in patients with diarrhoea and healthy individuals, ST4 appears to be epidemiologically linked to diarrhoea and/or chronic conditions such as irritable bowel syndrome (IBS).

There is no known efficient eradication strategy for Blastocystis. Although metronidazole is often prescribed for Blastocystis infections, there is conflicting reports on its efficacy. Even in combination with a luminal agent, such as paromomycin, Blastocystis eradication cannot be guaranteed. Read more here.

I'm very interested in studies aiming to explore
1) Blastocystis in the environment
2) Why some people are colonised while others are not
3) Whether Blastocystis colonisation requires a certain intestinal flora (e.g. enterotype) to establish
4) To which extent human Blastocystis is acquired from animal reservoirs
5) Potential differences in virulence between subtypes or strains (by for instance comparative genomic studies)

During my Blastocystis research, I and my colleagues have discovered/developed
1) New Blastocystis species
2) Precise molecular methods for accurate detection (PCR)
3) High resolution typing systems (MLST) for strain identification of Blastocystis
4) A standardised nomenclature for Blastocystis
5) A publicly available database for identification of subtypes and sequence data despository (please see links below)

Using microscopy-, culture-based and molecular tools we have generated data that have shed light over the transmission and distribution of Blastocystis subtypes in human and animals.


Translate

Contributors

  • ADTsaousis
  • Rune Stensvold
  • Unknown

 Subscribe in a reader

Search This Blog

Total Pageviews

Popular Posts

  • The Circular Problem of Blastocystis
    After submitting stool samples for microbiological analyses, many people with intestinal symptoms are informed by their GPs that they ...
  • Blastocystis - 'Monsters Inside Me'
    I woke up this morning, grabbed my smartphone and went on to check my Blastocystis Google Alert. There was one entry, and this was the on...
  • Amelioration of Colitis by Parasites - or "An Elliott & Weinstock Special"
    Common parasites such as Blastocystis and Dientamoeba fragilis are often incriminated of causing chronic or intermittent diarrhoea o...
  • Dying to know about Dientamoeba?
    It's difficult to say ' Blastocystis ' without saying ' Dientamoeba fragilis '. Both parasites tend to be extremely ...
  • This Month in Blastocystis Research (NOV 2014): Blasting Blastocystis Edition
    The 'This Month' post is triggered by a paper emerging in the journal Gut Pathogens describing a clinical pilot study on the effic...
  • Wrap-Up of Cell Symposium on Microbiome and Host Health
    For a parasitologist with a major interest in novel technology like me the Cell Symposium on Microbiome and Host Health (#CMHH) was a ...
  • To Treat or Not To Treat... But How?
    In the "To Treat or Not To Treat" series (please look up previous post here ), we have come to the "...But How?"...

Twitter

Tweets by Blastocystis

Find me on Facebook


Blog Archive

  • ▼  2023 (2)
    • ▼  May (1)
      • PhD Fellowship in Intestinal Microbiome Analysis a...
    • ►  February (1)
  • ►  2022 (7)
    • ►  December (1)
    • ►  September (1)
    • ►  July (2)
    • ►  May (1)
    • ►  February (1)
    • ►  January (1)
  • ►  2021 (12)
    • ►  December (1)
    • ►  July (1)
    • ►  June (2)
    • ►  May (3)
    • ►  April (2)
    • ►  March (1)
    • ►  January (2)
  • ►  2020 (5)
    • ►  November (2)
    • ►  February (1)
    • ►  January (2)
  • ►  2019 (11)
    • ►  December (1)
    • ►  November (1)
    • ►  October (2)
    • ►  June (1)
    • ►  May (1)
    • ►  April (3)
    • ►  March (1)
    • ►  February (1)
  • ►  2018 (16)
    • ►  December (2)
    • ►  November (1)
    • ►  October (3)
    • ►  August (1)
    • ►  July (3)
    • ►  June (2)
    • ►  March (2)
    • ►  February (2)
  • ►  2017 (5)
    • ►  October (1)
    • ►  September (1)
    • ►  July (1)
    • ►  April (1)
    • ►  March (1)
  • ►  2016 (12)
    • ►  December (2)
    • ►  November (1)
    • ►  September (2)
    • ►  August (1)
    • ►  July (1)
    • ►  June (1)
    • ►  May (1)
    • ►  April (1)
    • ►  March (1)
    • ►  January (1)
  • ►  2015 (18)
    • ►  December (2)
    • ►  November (1)
    • ►  October (1)
    • ►  September (1)
    • ►  July (2)
    • ►  June (2)
    • ►  May (3)
    • ►  April (1)
    • ►  March (1)
    • ►  February (4)
  • ►  2014 (27)
    • ►  December (1)
    • ►  November (1)
    • ►  October (2)
    • ►  September (1)
    • ►  August (3)
    • ►  July (2)
    • ►  June (2)
    • ►  May (5)
    • ►  April (2)
    • ►  March (2)
    • ►  February (4)
    • ►  January (2)
  • ►  2013 (45)
    • ►  December (3)
    • ►  November (3)
    • ►  October (2)
    • ►  September (4)
    • ►  August (1)
    • ►  July (4)
    • ►  June (2)
    • ►  May (6)
    • ►  April (8)
    • ►  March (6)
    • ►  February (4)
    • ►  January (2)
  • ►  2012 (57)
    • ►  December (2)
    • ►  November (3)
    • ►  October (3)
    • ►  September (2)
    • ►  August (3)
    • ►  July (7)
    • ►  June (10)
    • ►  May (4)
    • ►  April (13)
    • ►  March (10)

Useful Links & Blogroll

  • Animal and Human Parasite Images
  • Ascaris homepage
  • Atlas of Human Intestinal Protozoa
  • Blastocystis entry in Wikipedia
  • Blastocystis resource by CDC
  • Blastocystis Sequencing Typing Home Page
  • Cell Press Discussions
  • Creepy, Dreadful, Wonderful Parasites
  • Danish Society for Parasitology
  • Denim & Tweed
  • Entamoeba Home Page
  • European Society of Clinical Microbiology and Infectious Diseases
  • Genomes Unzipped
  • Gut Microbiota Watch
  • Infection Landscapes
  • International Society of Protistologists
  • Microbe Magazine
  • microBEnet
  • Microbiology Blogs @ MicroBEnet
  • nature.com blogs
  • Parasite Image Library @ CDC
  • Parasite of The Day
  • Parasites - Talk Parasites Blog
  • Phenomena - National Geographic
  • PubMed
  • Statens Serum Institut
  • The Molecular Ecologist
  • The Ocelloid
  • The Parasitologist
  • The Royal Society - Invigorate
  • The Tree of Life
  • United European Gastroenterology Library

This Week in Parasitism

Loading...

Portals

Christen Rune Stensvold ResearchBlogging.org

Labels

  • @Blastocystis
  • @Blastocystis; IBN
  • @Blastocystis21
  • @i_blasto
  • #Blastocystis
  • #thenetherlands
  • #UEGEducation
  • #UEGWeek
  • 16S
  • 18S
  • 18S allele
  • 1st International Blastocystis Symposium
  • 2014
  • 2018
  • 2022
  • 2nd International Blastocystis Conference
  • 3rd International Blastocystis Conference
  • adaptation
  • Africa
  • age
  • AIDS
  • allele
  • allergy
  • Alternative Oxidase
  • Amazon
  • America
  • Amoebozoa
  • amoxicillin
  • amplicon-based sequencing
  • animal models
  • animals
  • Ankara
  • anniversary
  • annual meeting
  • antibiotic resistance
  • antibiotics
  • ape
  • app
  • archaea
  • article
  • artwork
  • Asia
  • ASM
  • ASM2012
  • ASM2014
  • asymptomatic
  • ATCC
  • Australia
  • autoimmune disease
  • bacteria
  • bacteriotherapy
  • bactrim
  • barcode region
  • barcoding
  • Bella Center
  • beneficial microbes
  • Bioinformatics
  • biomarker
  • BIONmeta
  • bird droppings
  • birds
  • BLAST
  • Blastocystis
  • Blastocystis hominis
  • Blastocystis meeting
  • Blastocystis music
  • Blastocystis network
  • Blastocystis Research
  • Blastocystis Sequence Typing Home Page
  • Blastocystis; IBN
  • blog
  • blog feed
  • Blog feedback
  • Bo
  • Bogotá
  • Brazil
  • bugs as drugs
  • cancer
  • canids
  • Canterbury
  • career
  • career portrait
  • career trajectory
  • casecontrol
  • cat
  • cats
  • cattle
  • CDD
  • cell
  • Cell biology
  • children
  • clinical microbiology
  • Clioquinol
  • cloning
  • Clostridium difficile
  • co-evolution
  • co-infection
  • co-trimoxazole
  • coffee
  • colitis
  • Colombia
  • colonisation
  • commensal
  • commercial kits
  • committees
  • companion animals
  • comparison
  • Conference
  • Congress
  • controversial pathogens
  • Copenhagen
  • cotrimoxazole
  • Crete
  • Crohn's Disease
  • cryopreservation
  • Cryptosporidium
  • culture
  • cyst
  • cysteine protease
  • Dante
  • data mining
  • database
  • debate
  • Denmark
  • Dermatology
  • diagnosis
  • diagnostics
  • diarrhoea
  • Dientamoeba
  • Dientamoeba fragilis
  • Diet
  • differential diagnosis
  • digestion
  • diloxanide furoate
  • discussion
  • disease
  • division
  • DNA
  • dog
  • dogs
  • doxycyclin
  • drug
  • Drug discovery
  • dysbiosis
  • dyspepsia
  • e-learning
  • eBook
  • ECCMID
  • ECCMID2020
  • ecology
  • education
  • email subscription
  • Endolimax
  • endosymbionts
  • Entamoeba
  • enterocytes
  • enterotype
  • epidemiology
  • ESCMID
  • eubiosis
  • Eukaryome
  • Eukaryotic Community Analysis
  • Eukaryotome
  • Europe
  • evolution
  • evolutionary biology
  • experimental models
  • EzineArticles
  • Facebook
  • Faecal Microbiota Transplantation
  • faecal transplant
  • Fasting
  • Fellowship
  • Field Work
  • FMT
  • fomites
  • food microbiology
  • foodborne transmission
  • free articles
  • Frontiers
  • functional dyspepsia
  • Funding
  • fungi
  • furazolidone
  • gastroenterology
  • GenBank
  • genetic diversity
  • genetic diversity database subtype species ribosomal lineage taxonomy host specificity Blastocystis Entamoeba reference data
  • genome
  • genomics
  • genotype
  • Giardia
  • global
  • Google
  • Greece
  • guano
  • guidelines
  • gut
  • gut ecology
  • gut flora
  • gut microbiome
  • gut microbiota
  • gut mucosa
  • health
  • healthy individuals
  • Helicobacter pylori
  • helminth
  • helminth therapy
  • histology
  • HIV
  • HMP
  • horizontal gene transfer
  • host specificity
  • human health and disease
  • humatin
  • hygiene hypothesis
  • Hypoxia
  • ibd
  • IBN
  • IBS
  • ICOP
  • ICOPA
  • ICOPA2022
  • ICOPAnhagen
  • icopnhagen
  • IFA
  • immunity
  • Immunology
  • immunomodulation
  • immunosuppresion
  • India
  • infection
  • inflammation
  • inflammatory bowel disease
  • International
  • International Blastocystis Network
  • invasiveness
  • Iodamoeba
  • iPhone
  • iPhone adaptor
  • Iraq
  • irritable bowel syndrome
  • JCM
  • job
  • Kindle
  • Kioloa Coastal Campus
  • lab animals
  • laboratory analyses
  • lateral gene transfer; adaptation
  • lemur
  • Libya
  • life cycle
  • London School of Hygiene and Tropical Medicine
  • LSHTM
  • LUMINEX
  • M-SHIME
  • macaque
  • Malawi
  • MaldiTof
  • Mark van der Giezen
  • meeting
  • metagenomics
  • MetaHIT
  • methanoarchaeon
  • methodology
  • metronidazole
  • mexico
  • Mexico City
  • micro-eukaryote
  • microbiology
  • microbiome
  • microbiota
  • microbiota diversity
  • microorganisms
  • microscopy
  • mitochondrion-like organelle
  • MLST
  • molecular epidemiology
  • monkey
  • morphology
  • Most popular posts
  • MSc
  • mucin
  • music
  • mutualism
  • mycobiome
  • mycology
  • nematode
  • neutrophils
  • New Year
  • next generation sequencing
  • NGO
  • NGS
  • NIH
  • nitazoxanide
  • non-human primates
  • Norway
  • nutrition
  • obesity
  • Oceania
  • One Health
  • online course
  • open access
  • opportunistic eukaryotes
  • Oxygen
  • pageviews
  • parasite
  • Parasite Epidemiology and Control
  • parasite load
  • parasites
  • parasitism
  • Parasitology
  • Parasitology Course
  • Paris
  • paromomycin
  • pathology
  • PCR
  • Persian Gulf
  • pets
  • PhD
  • PhD position
  • phylogeny
  • pig
  • pig model
  • pinworm
  • podcast
  • poll
  • polyparasitism
  • PopSci
  • post doc
  • practical information
  • prebiotics
  • Prevalence
  • probiotics
  • proposal
  • protease
  • protist
  • protistology
  • protocol
  • protozoa
  • protozoology
  • Public Health
  • Public Health Microbiology
  • publication
  • Publications
  • PubMed
  • PubMLST
  • pyrosequencing
  • Qatar
  • quality control
  • R&D
  • rat model
  • RCT
  • real-time PCR
  • reference data
  • reference sequences
  • reproduction
  • research
  • research ethics
  • research focus
  • Research Topic
  • review
  • ribosomal lineage
  • rickettsia
  • Rome III criteria
  • Russia
  • Saccharomyces
  • Sample Preservation
  • sampling
  • Scandinavian-Baltic Society for Parasitology
  • scientific article
  • screening
  • secnidazole
  • septrim
  • sequence analysis
  • sequence type
  • Sequencing
  • sheep
  • Skin diseases
  • Social network
  • Society
  • software
  • SOP
  • South America
  • special issue
  • SSI
  • SSU rDNA
  • SSU rRNA gene
  • ST1
  • ST10
  • ST2
  • ST3
  • ST4
  • ST5
  • ST9
  • standard
  • standardisation
  • Statens Serum Institut
  • Stavanger
  • stramenopiles
  • STS
  • STS primers
  • subtype
  • subtypes
  • subtyping
  • summary
  • susceptibility
  • symposium
  • symptom
  • symptomatic
  • syndemism
  • T cells
  • Take-home messages
  • taxonomy
  • TB
  • testing
  • tetracycline
  • Thoughts on Blastocystis
  • tolerance
  • tradition
  • transcriptome
  • transcriptomics
  • transmission
  • travel
  • Treatment
  • trends in parasitology
  • trichomonad
  • trichrome staining
  • Trichuris
  • Triple Therapy
  • Tropical Medicine and International Health
  • tropical parasitology
  • tropism
  • tuberculosis
  • Turkey
  • tutorial
  • Twitter
  • typing
  • UAE
  • UEG
  • UEG Education
  • UEG Week
  • UK
  • ulcerative colitis
  • United European Gastroenterology
  • urticaria
  • USA
  • vegetables
  • veterinary medicine
  • video
  • virotherapy
  • Virtual
  • virtual conference
  • virulence
  • virus
  • water
  • website
  • WFP
  • wildlife
  • Wonderful Copenhagen
  • Workshop
  • World Digestive Health Day
  • World Federation for Parasitologists
  • yeast
  • YouTube
  • zoo
  • Zoonosis

LinkedIn

View Christen Rune Stensvold's profile on LinkedIn

Subscribe To

Posts
Atom
Posts
All Comments
Atom
All Comments
Powered by Blogger.